SCHEMBL16451697

SCHEMBL16451697

c1ccc(-c2cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)c6)c5c43)cc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
PTGER4 P35408 1/20 0.34
KMT2A Q03164 3/20 0.32
GAA P10253 2/20 0.32
MEN1 O00255 2/20 0.32
NPY5R Q15761 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSPO P30536 1/20 0.31
IL1R1 P14778 1/20 0.30
LMNA P02545 1/20 0.30
PTGES O14684 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
PDE10A Q9Y233 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24164194 0.91 ATM (0.40) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL24164222 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL16674012 0.90 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL24164184 0.89 ATM (0.36) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL24164227 0.89 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL24164223 0.89 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL24164224 0.88 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AGAA
SCHEMBL16674192 0.87 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16260437 0.87 L3MBTL1 (0.39) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16675129 0.86 KDM4E (0.40) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9985219-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-9985219-B2 Organic electroluminescent element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-05-29 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed
US-20150041785-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-02-12 US disclosed