Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644432 | 0.89 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3ALDH1A1MAPT | |
| SCHEMBL1645157 | 0.88 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1644194 | 0.88 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1645804 | 0.86 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1644224 | 0.84 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1645487 | 0.84 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3MAPTTDP1 | |
| SCHEMBL1644437 | 0.84 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1644198 | 0.83 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3ALDH1A1MAPT | |
| SCHEMBL1644221 | 0.83 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL5833101 | 0.83 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-04-28 | — | — | US | disclosed |
| EP-1519917-A4 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | UNIV COLUMBIA (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1519917-A2 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-04-06 | — | — | EP | disclosed |
| WO-2003096978-A2 | CARBON-11 AND FLUORINE-18 LABELED RADIOLIGANDS FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING FOR THE BRAIN SEROTONIN TRANSPORTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097274-A1 | Carbon-11 and fluorine-18 labeled radioligands for positron emission tomography (PET) imaging for the brain serotonin transporters | SLC6A4, SLC18A2, SLC6A2 | SLC6A4 1/4885SLC6A2 3/4885SLC6A3 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.