Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645487 | 0.86 | SLC6A4 (0.64) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1644437 | 0.86 | SLC6A4 (0.64) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1644221 | 0.85 | SLC6A4 (0.69) | SLC6A4SLC6A2LMNASLC6A3PDE7A | |
| SCHEMBL236212 | 0.85 | SLC6A4 (0.64) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1645176 | 0.83 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL1645157 | 0.83 | SLC6A4 (0.64) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1644194 | 0.83 | SLC6A4 (0.65) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1645804 | 0.81 | SLC6A4 (0.66) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL1644224 | 0.79 | SLC6A4 (0.67) | SLC6A4SLC6A2LMNASLC6A3TDP1 | |
| SCHEMBL2746964 | 0.79 | SLC6A4 (0.56) | SLC6A4SLC6A2LMNASLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096623-B1 | Method for preparing radiotracer precursor SnADAM | Atomic Energy Council—Institute of Nuclear Energy Research (TW) | 2015-08-04 | — | — | US | disclosed |
| US-7041851-B2 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-05-09 | — | — | US | disclosed |
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR | 2003-12-25 | — | — | US | disclosed |
| WO-2003078393-A2 | FLUORINATED PHENYL THIOPHENYL DERIVATIVES AND THEIR USE FOR IMAGING SEROTONIN TRANSPORTERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236234-A1 | Fluorinated phenyl thiophenyl derivatives and their use for imaging serotonin transporters | SLC6A4, SLCO4C1, SLC6A2 | SLC6A4 1/4885SLC6A2 3/4885SMN1; SMN2 3426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.