Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16453144 | 0.93 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL16453195 | 0.86 | SCNN1A (0.49) | SCNN1A | |
| SCHEMBL20683800 | 0.83 | SCNN1A (0.54) | SCNN1A | |
| SCHEMBL16453284 | 0.83 | SCNN1A (0.54) | SCNN1A | |
| Hydrochloric Acid SCHEMBL16443777 | 0.83 | SCNN1A (0.54) | SCNN1A | |
| Hydrochloric Acid SCHEMBL16443778 | 0.83 | SCNN1A (0.54) | SCNN1A | |
| Hydrochloric Acid SCHEMBL16443779 | 0.83 | SCNN1A (0.54) | SCNN1A | |
| SCHEMBL20683785 | 0.82 | SCNN1A (0.48) | SCNN1A | |
| SCHEMBL20683744 | 0.78 | SCNN1A (0.42) | SCNN1A | |
| SCHEMBL16443690 | 0.77 | SCNN1A (0.54) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030555-B1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2019-01-30 | — | — | EP | disclosed |
| WO-2015018754-A1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-12 | — | — | WO | disclosed |