Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454853 | 0.92 | ALDH1A1 (0.46) | KCNK3KCNK9KMT2APOLBPKM | |
| SCHEMBL16454829 | 0.90 | KCNK3 (0.49) | KCNK3KCNK9KMT2APOLBRAB9A | |
| SCHEMBL16454812 | 0.88 | MAPT (0.49) | KCNK3KCNK9KMT2APOLBRAB9A | |
| SCHEMBL16454827 | 0.86 | IDO1 (0.48) | KMT2ARAB9AGAANPC1HPGD | |
| SCHEMBL16454784 | 0.83 | TSHR (0.46) | KMT2APOLBRAB9AGAASMN1; SMN2 | |
| SCHEMBL16454888 | 0.83 | KCNK3 (0.50) | KCNK3KCNK9L3MBTL1STAT3KMT2A | |
| SCHEMBL16454876 | 0.83 | NPC1 (0.55) | KCNK3KCNK9L3MBTL1STAT3KMT2A | |
| SCHEMBL16454869 | 0.82 | KMT2A (0.49) | KMT2APOLBRAB9AGAASMN1; SMN2 | |
| SCHEMBL16454789 | 0.81 | CHRNA7 (0.44) | KCNK3KCNK9L3MBTL1KMT2APOLB | |
| SCHEMBL16454809 | 0.81 | TSHR (0.53) | KMT2APOLBRAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |