SCHEMBL16455170 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	2/20	0.45

▸	MTTP	P55157	2/20	0.44

▸	CD274	Q9NZQ7	1/20	0.43

▸	KDM1A	O60341	3/20	0.43

▸	HIF1A	Q16665	1/20	0.43

▸	EPAS1	Q99814	1/20	0.43

▸	F2	P00734	1/20	0.43

▸	AKR1C3	P42330	1/20	0.41

▸	TACR1	P25103	2/20	0.41

▸	PIN1	Q13526	1/20	0.41

▸	HDAC4	P56524	1/20	0.41

▸	HDAC6	Q9UBN7	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20924673	0.90	KDM1A (0.51)	KDM1A
SCHEMBL18848759	0.89	F2 (0.49)	EPHX2MTTPCD274KDM1AHIF1A
SCHEMBL19634217	0.82	KDM1A (0.44)	EPHX2MTTPCD274KDM1A
SCHEMBL18059527	0.81	KDM1A (0.59)	KDM1A
SCHEMBL19466069	0.81	KDM1A (0.59)	KDM1A
SCHEMBL16447254	0.78	KDM1A (0.53)	KDM1APIN1
SCHEMBL16447253	0.78	KDM1A (0.53)	KDM1APIN1
SCHEMBL16455163	0.78	KDM1A (0.53)	CD274KDM1APIN1
SCHEMBL16447281	0.77	KDM1A (0.51)	KDM1A
SCHEMBL16447279	0.77	KDM1A (0.51)	KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015021128-A1	KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE	IMAGO BIOSCIENCES INC. (US)	2015-02-12	—	—	WO	disclosed