Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455170 | 0.90 | EPHX2 (0.45) | KDM1A | |
| SCHEMBL16447254 | 0.88 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16455163 | 0.88 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16447253 | 0.88 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16447279 | 0.87 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16447281 | 0.87 | KDM1A (0.51) | KDM1A | |
| SCHEMBL16455182 | 0.84 | KDM1A (0.53) | KDM1A | |
| SCHEMBL16447050 | 0.83 | KDM1A (0.64) | KDM1A | |
| SCHEMBL18848760 | 0.83 | KDM1A (0.64) | KDM1A | |
| SCHEMBL16447052 | 0.83 | KDM1A (0.64) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030323-B1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC (US) | 2019-04-24 | — | — | EP | disclosed |