Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 17/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455030 | 0.91 | UGCG (0.51) | UGCGKDM1ACYP2D6 | |
| SCHEMBL16455198 | 0.90 | KDM1A (0.48) | UGCGKDM1A | |
| SCHEMBL16455120 | 0.89 | UGCG (0.49) | UGCGKDM1A | |
| SCHEMBL16455122 | 0.89 | UGCG (0.51) | UGCG | |
| SCHEMBL18848618 | 0.88 | KMT2A (0.51) | UGCGKDM1A | |
| SCHEMBL20781661 | 0.87 | KDM1A (0.44) | KDM1A | |
| SCHEMBL22856674 | 0.83 | KDM1A (0.59) | KDM1A | |
| SCHEMBL18848746 | 0.82 | KDM1A (0.58) | KDM1A | |
| SCHEMBL20781392 | 0.81 | KDM1A (0.49) | UGCGKDM1A | |
| SCHEMBL19634347 | 0.81 | KDM1A (0.71) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2015021128-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC. (US) | 2015-02-12 | — | — | WO | disclosed |