Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967877 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL5988485 | 0.76 | PARG (0.47) | MAPTALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL28284190 | 0.76 | MEN1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28171570 | 0.76 | MEN1 (0.44) | MAPTALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL6196774 | 0.76 | MEN1 (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30573352 | 0.76 | PARG (0.47) | MAPTALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL5990018 | 0.76 | CDC7 (0.47) | ALDH1A1MEN1KMT2APARP1CYP3A4 | |
| SCHEMBL3960657 | 0.76 | EGFR (0.67) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5989853 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL6594656 | 0.76 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015018356-A1 | DIARYLHYDANTOIN DERIVATIVE, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 上海医药集团股份有限公司 (CN) | 2015-02-12 | — | — | WO | disclosed |