Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093031 | 0.84 | ALDH1A1 (0.54) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL3642887 | 0.81 | NPC1 (0.52) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL28065059 | 0.80 | NPC1 (0.46) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL28109640 | 0.80 | MAPT (0.48) | POLBNPC1MAPTALDH1A1KDM4E | |
| SCHEMBL29638304 | 0.80 | MAPT (0.48) | POLBNPC1MAPTALDH1A1KDM4E | |
| SCHEMBL6776849 | 0.79 | MAPT (0.39) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL6776846 | 0.79 | MAPT (0.39) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL8130335 | 0.79 | NPC1 (0.50) | POLBNPC1MAPTRBP4ALDH1A1 | |
| SCHEMBL8123257 | 0.79 | EGFR (0.41) | ALDH1A1GAAKDM4EGLASIRT3 | |
| SCHEMBL28101840 | 0.79 | TDP1 (0.56) | NPC1ALDH1A1GAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105451558-A | Pyrazolyl pyrrolinones and their use as herbicides | SYNGENTA PARTICIPATIONS AG | 2016-03-30 | — | — | CN | disclosed |
| WO-2015018432-A1 | PYRROLONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |