Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.80 |
| ▸ | VDR | P11473 | 2/20 | 0.64 |
| ▸ | LIFR | P42702 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083938 | 0.94 | NR1H4 (0.80) | NR1H4VDRLIFR | |
| SCHEMBL1180454 | 0.89 | NR1H4 (1.00) | NR1H4VDRLIFR | |
| SCHEMBL1179789 | 0.88 | NR1H4 (1.00) | NR1H4LIFR | |
| SCHEMBL2083409 | 0.85 | NR1H4 (0.64) | NR1H4LIFR | |
| SCHEMBL16456790 | 0.85 | NR1H4 (0.64) | NR1H4VDRLIFR | |
| SCHEMBL1180127 | 0.84 | NR1H4 (1.00) | NR1H4LIFR | |
| SCHEMBL2084624 | 0.84 | NR1H4 (0.65) | NR1H4LIFR | |
| SCHEMBL1180458 | 0.83 | NR1H4 (0.83) | NR1H4VDRLIFR | |
| SCHEMBL1179413 | 0.83 | NR1H4 (1.00) | NR1H4LIFR | |
| SCHEMBL16456821 | 0.82 | NR1H4 (0.65) | NR1H4VDRLIFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984360-B1 | Compounds and methods for modulating FX-receptors | LILLY CO ELI (US) | 2014-01-15 | — | — | EP | disclosed |