Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | LIFR | P42702 | 1/20 | 0.57 |
| ▸ | VDR | P11473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083409 | 0.88 | NR1H4 (0.64) | NR1H4NR1I2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16456676 | 0.85 | NR1H4 (0.80) | NR1H4LIFRVDR | |
| SCHEMBL2083938 | 0.85 | NR1H4 (0.80) | NR1H4LIFRVDR | |
| SCHEMBL2084624 | 0.85 | NR1H4 (0.65) | NR1H4LIFR | |
| SCHEMBL16456821 | 0.83 | NR1H4 (0.65) | NR1H4LIFRVDR | |
| SCHEMBL2084127 | 0.82 | NR1H4 (0.65) | NR1H4LIFRVDR | |
| SCHEMBL16456695 | 0.82 | NR1H4 (0.70) | NR1H4CYP1A2CYP2C9LIFRVDR | |
| SCHEMBL16456784 | 0.82 | NR1H4 (0.64) | NR1H4LIFR | |
| SCHEMBL16456725 | 0.81 | NR1H4 (0.60) | NR1H4LIFR | |
| SCHEMBL16456707 | 0.81 | NR1H4 (0.62) | NR1H4LIFRVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984360-B1 | Compounds and methods for modulating FX-receptors | LILLY CO ELI (US) | 2014-01-15 | — | — | EP | disclosed |