SCHEMBL16456852

SCHEMBL16456852

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nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10511032 0.76 TDP1 (0.46) TDP1
SCHEMBL10509917 0.76 TDP1 (0.46) TDP1
SCHEMBL10509129 0.76 TDP1 (0.46) TDP1
SCHEMBL3630267 0.76 TDP1 (0.46) TDP1
SCHEMBL10733105 0.76 TDP1 (0.46) TDP1
SCHEMBL10734940 0.76 TDP1 (0.46) TDP1
SCHEMBL8208717 0.76 TDP1 (0.46) TDP1
SCHEMBL10507358 0.76 TDP1 (0.46) TDP1
SCHEMBL1534006 0.76 TDP1 (0.46) TDP1
SCHEMBL10508529 0.76 TDP1 (0.46) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2282773-B2 METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION SEAGEN INC (US) 2025-03-05 — — EP disclosed
EP-3513794-A2 FUCOSE ANALOGS FOR INHIBITION OF PROTEIN FUCOSYLATION IN VIVO Seattle Genetics, Inc. (US) 2019-07-24 — — EP disclosed
EP-2608796-B1 INHIBITION OF PROTEIN FUCOSYLATION IN VIVO USING FUCOSE ANALOGS SEATTLE GENETICS INC (US) 2018-11-21 — — EP disclosed
EP-2282773-B1 METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION SEATTLE GENETICS INC (US) 2014-01-15 — — EP disclosed
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