Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509129 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10507358 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL17748350 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL1534006 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10733105 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10734940 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10509917 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10508529 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL3630267 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL10511032 | 1.00 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115708883-A | Macrophage nanoparticle compound and preparation method and application thereof | 珠海中科先进技术研究院有限公司 | 2023-02-24 | — | — | CN | claimed |
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-05 | — | — | US | claimed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | claimed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | claimed |
| US-12576155-B2 | Senolytic and antiinflammatory prodrugs and methods of use thereof | PEKING UNIVERSITY (CN) | 2026-03-17 | — | — | US | disclosed |
| WO-2024036961-A1 | PRODRUG FOR ANTI-AGING RELATED DISEASES AND USE METHOD THEREFOR | 北京三秀生物医药科技有限公司 | 2024-02-22 | — | — | WO | disclosed |
| CN-114341148-B | Anti-aging and anti-inflammatory prodrugs and methods of use thereof | 北京大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-115708883-A | Macrophage nanoparticle compound and preparation method and application thereof | 珠海中科先进技术研究院有限公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20220362387-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2022-11-17 | — | — | US | disclosed |
| CN-114341148-A | Anti-aging and anti-inflammatory prodrugs and methods of use thereof | 北京大学 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021057061-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021056270-A1 | SENOLYTIC PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| US-5530123-A | ANTIVIRAL AND CHEMOTHERAPEUTICAL AGENT FOR CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-06-25 | — | — | US | disclosed |
| US-5457195-A | Sapphyrin derivatives and conjugates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-10-10 | — | — | US | disclosed |
| WO-1994009003-A1 | SAPPHYRIN DERIVATIVES, CONJUGATES AND POLYMERS THEREOF AND EXPANDED PORPHYRIN CHROMATOGRAPHIC SUPPORTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-28 | — | — | WO | disclosed |
| EP-0173462-B1 | ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF | SUNTORY LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4698423-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0173462-A2 | Ellipticine derivative and production process thereof | SUNTORY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |
| US-4563445-A | DETECTION OF GASTROINTESTINAL | CHOAY S.A. (FR) | 1986-01-07 | — | — | US | disclosed |
| EP-0069678-A2 | 3-Fucosyl-N-acetyl-lactosamine derivatives, their preparation and their biological applications | CHOAY S.A. (FR) | 1983-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576155-B2 | Senolytic and antiinflammatory prodrugs and methods of use thereof | GLA, SENP6, GLB1 | TDP1 271/4885TSHR 1161/4885TRPV1 4548/4885 |
| US-20220362387-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | GLA, SENP6, GLB1 | TDP1 468/4885TSHR 2848/4885TRPV1 4102/4885 |
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | ST6GAL1, B4GALT1, GALNT6 | TDP1 2029/4885TSHR 191/4885TRPV1 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.