Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456865 | 0.92 | NR3C2 (0.59) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL16456984 | 0.91 | NR3C2 (0.65) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL2359769 | 0.91 | NR3C2 (0.46) | NR3C2MAPTTP53AVPR2ALDH1A1 | |
| SCHEMBL16456941 | 0.91 | NR3C2 (0.60) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL16456985 | 0.90 | NR3C2 (0.58) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL2547086 | 0.89 | NR3C2 (0.48) | NR3C2LMNAMAPTAVPR2ALDH1A1 | |
| SCHEMBL16457251 | 0.86 | NR3C2 (0.60) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL16457039 | 0.86 | NR3C2 (0.62) | NR3C2LMNAMAPTTP53GPR27 | |
| SCHEMBL2358752 | 0.85 | NR3C2 (0.74) | NR3C2GPR27AVPR2PTGS2MAOA | |
| SCHEMBL16456888 | 0.85 | NR3C2 (0.61) | NR3C2LMNAMAPTTP53GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |