Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456984 | 0.90 | NR3C2 (0.65) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL16456946 | 0.90 | NR3C2 (0.56) | NR3C2AVPR2GPR27RORCLMNA | |
| SCHEMBL16456865 | 0.88 | NR3C2 (0.59) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL2357097 | 0.87 | NR3C2 (0.67) | NR3C2AVPR2GPR27RORCKCNK3 | |
| SCHEMBL16457039 | 0.85 | NR3C2 (0.62) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL16456888 | 0.84 | NR3C2 (0.61) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL2359256 | 0.83 | NR3C2 (0.75) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL16456961 | 0.83 | NR3C2 (0.60) | NR3C2AVPR2GPR27LMNATP53 | |
| SCHEMBL16458357 | 0.83 | NR3C2 (0.61) | NR3C2AVPR2GPR27LMNAPTGS2 | |
| SCHEMBL16456941 | 0.82 | NR3C2 (0.60) | NR3C2AVPR2GPR27LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |