Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105010 | 1.00 | ROCK2 (0.77) | ROCK2ROCK1 | |
| SCHEMBL111949 | 0.85 | ROCK2 (0.80) | ROCK2ROCK1 | |
| SCHEMBL21514529 | 0.84 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL21514522 | 0.84 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL2775991 | 0.84 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL15047834 | 0.83 | ROCK2 (0.74) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL31651002 | 0.83 | ROCK2 (0.98) | ROCK2ROCK1 | |
| SCHEMBL2776982 | 0.83 | ROCK2 (0.72) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL2780306 | 0.82 | ROCK2 (0.71) | ROCK2ROCK1 | |
| SCHEMBL112543 | 0.81 | ROCK2 (0.72) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326623-B1 | BETA-AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS | AERIE PHARMACEUTICALS INC (US) | 2014-04-16 | — | — | EP | disclosed |