Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456919 | 0.92 | NR3C2 (0.59) | NR3C2GRM5GPR27AVPR2LMNA | |
| SCHEMBL2356953 | 0.89 | NR3C2 (0.62) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL16458357 | 0.88 | NR3C2 (0.61) | NR3C2GPR27AVPR2LMNAALDH1A1 | |
| SCHEMBL16457018 | 0.87 | NR3C2 (0.59) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL16458360 | 0.87 | NR3C2 (0.68) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL16458359 | 0.87 | NR3C2 (0.64) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL16456865 | 0.86 | NR3C2 (0.59) | NR3C2GRM5GPR27AVPR2LMNA | |
| SCHEMBL2359867 | 0.86 | NR3C2 (0.73) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL2359492 | 0.85 | NR3C2 (0.75) | NR3C2GPR27AVPR2LMNAMAPT | |
| SCHEMBL2359184 | 0.85 | NR3C2 (0.71) | NR3C2GPR27AVPR2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |