Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.61 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356953 | 0.90 | NR3C2 (0.62) | NR3C2TRPV4ALDH1A1LMNAHTT | |
| SCHEMBL16458360 | 0.88 | NR3C2 (0.68) | NR3C2TRPV4ALDH1A1LMNAHTT | |
| SCHEMBL16458359 | 0.88 | NR3C2 (0.64) | NR3C2ALDH1A1LMNAHTTAVPR2 | |
| SCHEMBL16457201 | 0.88 | NR3C2 (0.58) | NR3C2ALDH1A1LMNAHTTAVPR2 | |
| SCHEMBL2359546 | 0.85 | NR3C2 (0.61) | NR3C2TRPV4ALDH1A1LMNAHTT | |
| SCHEMBL27997510 | 0.83 | NR3C2 (0.51) | NR3C2TRPV4ALDH1A1LMNAHTT | |
| SCHEMBL2359492 | 0.83 | NR3C2 (0.75) | NR3C2TRPV4ALDH1A1LMNAHTT | |
| SCHEMBL16456985 | 0.83 | NR3C2 (0.58) | NR3C2LMNAAVPR2GPR27PTGS2 | |
| SCHEMBL16456919 | 0.82 | NR3C2 (0.59) | NR3C2ALDH1A1LMNAHTTAVPR2 | |
| SCHEMBL16457018 | 0.82 | NR3C2 (0.59) | NR3C2ALDH1A1LMNAHTTAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |