Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006858 | 0.77 | MCHR1 (0.38) | GRM5MCHR1BAZ2B | |
| SCHEMBL1004240 | 0.69 | GRM5 (0.46) | GRM5MCHR1BAZ2B | |
| SCHEMBL9931576 | 0.68 | MCHR1 (0.43) | MCHR1BAZ2B | |
| SCHEMBL1004761 | 0.67 | DDB1 (0.40) | GRM5 | |
| SCHEMBL30339918 | 0.67 | DDB1 (0.40) | GRM5 | |
| SCHEMBL24102117 | 0.63 | NR3C1 (0.40) | BAZ2B | |
| SCHEMBL30340260 | 0.63 | NR3C1 (0.40) | BAZ2B | |
| SCHEMBL989561 | 0.62 | MCHR1 (0.38) | MCHR1BAZ2B | |
| SCHEMBL9930853 | 0.61 | DDB1 (0.47) | MCHR1BAZ2B | |
| SCHEMBL3476808 | 0.61 | BAZ2B (0.53) | GRM5BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448585-B1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RES INC (US) | 2014-01-01 | — | — | EP | disclosed |