Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 12/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 9/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 9/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16458137 | 1.00 | KCNA5 (0.55) | KCNA5KCNJ5KCNJ3P2RX7 | |
| SCHEMBL12081205 | 0.86 | KCNA5 (0.65) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080339 | 0.86 | KCNA5 (0.65) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL16458096 | 0.85 | KCNA5 (0.55) | KCNA5KCNJ5KCNJ3P2RX7 | |
| SCHEMBL16457840 | 0.85 | KCNA5 (0.55) | KCNA5KCNJ5KCNJ3P2RX7 | |
| Hydrochloric Acid SCHEMBL12079956 | 0.80 | KCNA5 (0.76) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12080169 | 0.80 | KCNA5 (0.61) | KCNA5KCNJ5KCNJ3P2RX7 | |
| SCHEMBL12081143 | 0.80 | KCNA5 (0.57) | KCNA5KCNJ5KCNJ3P2RX7 | |
| SCHEMBL15986297 | 0.80 | KCNA5 (0.57) | KCNA5KCNJ5KCNJ3P2RX7 | |
| Hydrochloric Acid SCHEMBL12080970 | 0.80 | KCNA5 (0.74) | KCNA5KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-B9 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | OTSUKA PHARMA CO LTD (JP) | 2015-02-18 | — | — | EP | disclosed |
| EP-2467364-B1 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | OTSUKA PHARMA CO LTD (JP) | 2014-04-16 | — | — | EP | disclosed |