Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231073 | 0.91 | LMNA (0.39) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2231070 | 0.90 | LMNA (0.40) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1646815 | 0.89 | LMNA (0.40) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1645789 | 0.86 | LMNA (0.36) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1647782 | 0.82 | LMNA (0.40) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1644374 | 0.82 | LMNA (0.41) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2232559 | 0.82 | LMNA (0.42) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1646094 | 0.81 | LMNA (0.41) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2230727 | 0.81 | SMN1; SMN2 (0.42) | LMNAHTTSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2233955 | 0.80 | LMNA (0.40) | LMNAHTTSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |