Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456970 | 0.94 | NR3C2 (0.52) | NR3C2SLC1A3SLC1A2SLC1A1ELANE | |
| SCHEMBL16457142 | 0.93 | NR3C2 (0.54) | NR3C2SLC1A3SLC1A2SLC1A1TRPV4 | |
| SCHEMBL16456984 | 0.91 | NR3C2 (0.65) | NR3C2SLC1A3SLC1A2SLC1A1ELANE | |
| SCHEMBL16457080 | 0.89 | NR3C2 (0.46) | NR3C2ELANEMAPTTP53LRRK2 | |
| SCHEMBL16457052 | 0.88 | NR3C2 (0.49) | NR3C2SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL16456938 | 0.88 | NR3C2 (0.58) | NR3C2MAPTTP53LRRK2 | |
| SCHEMBL16457022 | 0.87 | NR3C2 (0.62) | NR3C2SLC1A3SLC1A2SLC1A1TRPV4 | |
| SCHEMBL2548279 | 0.87 | NR3C2 (0.67) | NR3C2ELANETRPV4CRACR2A | |
| SCHEMBL2359769 | 0.86 | NR3C2 (0.46) | NR3C2MAPTTP53LRRK2 | |
| SCHEMBL2547086 | 0.84 | NR3C2 (0.48) | NR3C2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |