Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457052 | 0.94 | NR3C2 (0.49) | NR3C2HSD11B1AVPR2OXTRAVPR1A | |
| SCHEMBL16456970 | 0.93 | NR3C2 (0.52) | NR3C2AVPR2OXTRAVPR1ASLC1A3 | |
| SCHEMBL16458046 | 0.93 | NR3C2 (0.52) | NR3C2SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL2547086 | 0.92 | NR3C2 (0.48) | NR3C2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL16456984 | 0.89 | NR3C2 (0.65) | NR3C2AVPR2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16457022 | 0.88 | NR3C2 (0.62) | NR3C2SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL16457242 | 0.87 | NR3C2 (0.48) | NR3C2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL2550462 | 0.87 | NR3C2 (0.69) | NR3C2HSD11B1MAPTLMNATP53 | |
| SCHEMBL16457250 | 0.86 | NR3C2 (0.44) | NR3C2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL2359769 | 0.85 | NR3C2 (0.46) | NR3C2AVPR2OXTRAVPR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |