SCHEMBL1645838

SCHEMBL1645838

C[C@@H](C(=O)O)N(C)CC#N

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 7/20 0.44
MAOB P27338 1/20 0.42
CYP1A2 P05177 2/20 0.37
MAPK1 P28482 1/20 0.37
TP53 P04637 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29955162 1.00 DPP4 (0.44) DPP4MAOBCYP1A2MAPK1TP53
SCHEMBL20963089 0.80 DPP4 (0.41) DPP4MAOBCYP1A2MAPK1TP53
SCHEMBL869340 0.80 DPP4 (0.41) DPP4MAOBCYP1A2MAPK1TP53
SCHEMBL29950583 0.78 MAOB (0.42) MAOBCYP1A2MAPK1
SCHEMBL19614398 0.78 DPP4 (0.40) DPP4MAOBCYP1A2MAPK1TP53
Water SCHEMBL439515 0.73
Water SCHEMBL439514 0.73
SCHEMBL30300869 0.72 NPSR1 (0.34)
SCHEMBL18980132 0.72
SCHEMBL6135565 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486003-A1 METHOD FOR ISOLATING METHYLGLYCINENITRILE-N,N-DIACETONITRILE BASF SE (DE) 2012-08-15 EP disclosed
US-20120184769-A1 METHOD FOR ISOLATING METHYLGLYCINENITRILE-N,N-DIACETONITRILE BASF SE (DE) 2012-07-19 US disclosed
WO-2011042836-A1 METHOD FOR ISOLATING METHYLGLYCINENITRILE-N,N-DIACETONITRILE BASF SE (DE) 2011-04-14 WO disclosed
EP-2308834-A1 Method for isolating methylglycine nitrile-N, N-diacetonitrile BASF SE (DE) 2011-04-13 EP disclosed