Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336121 | 1.00 | MEN1 (0.32) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL334845 | 0.85 | — | — | |
| SCHEMBL18049497 | 0.65 | CA1 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL10128117 | 0.65 | TAAR1 (0.38) | TAAR1 | |
| SCHEMBL4982796 | 0.64 | CA1 (0.41) | KMT2AMAPT | |
| SCHEMBL335618 | 0.64 | TXNRD1 (0.42) | MAPTNPSR1TAAR1 | |
| SCHEMBL18049467 | 0.64 | CA1 (0.41) | KMT2A | |
| SCHEMBL8719986 | 0.64 | CA1 (0.43) | KMT2A | |
| SCHEMBL19890006 | 0.64 | CA1 (0.40) | KMT2A | |
| SCHEMBL3784560 | 0.63 | CA1 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300476-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LTD (GB) | 2014-01-08 | — | — | EP | disclosed |