Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471989 | 0.97 | LMNA (0.66) | LMNAHRH3CYP2D6KDM4EMAPT | |
| SCHEMBL16459758 | 0.86 | LMNA (0.47) | LMNAHRH3CYP2D6MMP9KDM4E | |
| SCHEMBL16459397 | 0.84 | LMNA (0.46) | LMNAHRH3CYP2D6MMP9KDM4E | |
| SCHEMBL16460055 | 0.84 | LMNA (0.46) | LMNAHRH3CYP2D6KDM4EMAPT | |
| SCHEMBL16459040 | 0.84 | LMNA (0.46) | LMNAHRH3CYP2D6MMP9KDM4E | |
| SCHEMBL23480876 | 0.84 | LMNA (0.46) | LMNAHRH3CYP2D6KDM4EMAPT | |
| SCHEMBL16460189 | 0.84 | LMNA (0.50) | LMNALPLLIPGHRH3CYP2D6 | |
| SCHEMBL16459946 | 0.82 | LMNA (0.46) | LMNALPLLIPGKDM4ECHRNA1 | |
| SCHEMBL16459020 | 0.82 | MEN1 (0.45) | LMNAHRH3KDM4EMAPTESR2 | |
| SCHEMBL16459638 | 0.81 | LMNA (0.47) | LMNAHRH3KDM4ECHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | MINK1, MELK, MRPL21 | LMNA 1949/4885LPL 1112/4885LIPG 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.