SCHEMBL164597

SCHEMBL164597

COC(=O)c1cccc(C(=O)O)c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
LMNA P02545 3/20 0.52
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 4/20 0.51
HSD17B10 Q99714 3/20 0.50
CFTR P13569 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
MAPT P10636 2/20 0.49
ALOX15 P16050 1/20 0.49
POLB P06746 1/20 0.48
ATM Q13315 1/20 0.48
MYC P01106 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HPGD P15428 2/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
MAPK10 P53779 1/20 0.46
PTK2B Q14289 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3511612 0.92 LMNA (0.59) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL28684512 0.91 PTGER1 (0.52) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL2251430 0.89 TSHR (0.59) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL2004816 0.88 CA12 (0.47) TSHRLMNAALDH1A1KDM4EHSD17B10
Dimethyl Phthalate SCHEMBL31148829 0.86 TSHR (0.55) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL27703022 0.86 TSHR (0.55) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL27504961 0.85 TSHR (0.55) TSHRALDH1A1KDM4EPOLBSLC6A3
SCHEMBL756585 0.85 TSHR (0.61) TSHRLMNAALDH1A1KDM4EHSD17B10
Benzene SCHEMBL27265959 0.85 TSHR (0.61) TSHRLMNAALDH1A1KDM4EHSD17B10
SCHEMBL27703149 0.85 TSHR (0.61) TSHRLMNAALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4970100-A POLYESTER BLEND F. OBERDORFER GMBH & CO. KG INDUSTRIEGEWEBE-TECHNIK (DE) 1990-11-13 US claimed
JP-60149486-A None JP disclosed
US-20220325036-A1 PROCESS FOR THE PREPARATION OF POLYESTERS WITH RECYCLED MONOMERS FROM PYROLYSIS AND METHANOLYSIS EASTMAN CHEMICAL COMPANY (US) 2022-10-13 US disclosed
EP-4004094-A1 PROCESS FOR THE PREPARATION OF POLYESTERS WITH RECYCLED MONOMERS FROM PYROLYSIS AND METHANOLYSIS Eastman Chemical Company (US) 2022-06-01 EP disclosed
EP-3413134-B1 HYBRID TONER COMPOSITIONS XEROX CORP (US) 2021-12-22 EP disclosed
CN-113717356-A Semi-aromatic polyester and preparation method and application thereof 珠海万通化工有限公司 2021-11-30 CN disclosed
US-11048184-B2 Toner process employing dual chelating agents XEROX CORPORATION (US) 2021-06-29 US disclosed
WO-2021021902-A1 PROCESS FOR THE PREPARATION OF POLYESTERS WITH RECYCLED MONOMERS FROM PYROLYSIS AND METHANOLYSIS EASTMAN CHEMICAL COMPANY (US) 2021-02-04 WO disclosed
US-20200225598-A1 Toner Process Employing Dual Chelating Agents XEROX CORPORATION 2020-07-16 US disclosed
EP-3413134-A1 HYBRID TONER COMPOSITIONS Xerox Corporation (US) 2018-12-12 EP disclosed
WO-2007065288-A2 USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2007-06-14 WO disclosed
CN-1309463-C Dispersants AVECIA LTD (US) 2007-04-11 CN disclosed
CN-1823141-A Quinacridone pigment compositions comprising unsymmetrically substituted components CIBA SC HOLDING AG (CH) 2006-08-23 CN disclosed
CN-1531457-A Dispersants 2004-09-22 CN disclosed
CN-1007492-B TECHNOLOGY FOR RECIRCULATING USE OF CATALYST IDEMITSU PETROCHEMICAL CO (JP) 1990-04-11 CN disclosed
CN-87104325-A Catalyst circulation is used technology 1988-07-06 CN disclosed
JP-S60149486-A PRINTING METHOD ON MOLDED RESIN PRODUCT OF POLYOLEFIN GROUP TOUNEN SEKIYU KAGAKU KK 1985-08-06 JP disclosed
EP-0105826-A1 Polyester melt blends having high gas barrier properties THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-04-18 EP disclosed
US-RE30783-E WHEREIN A PHOSPHINIC ACID MONOMER IS INCORPORATED INTO THE POLYESTER HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-3941752-A Flame retarding linear polyesters and shaped articles thereof HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-02 US disclosed