Methane

Methane

SCHEMBL16463501

C.NP(O)(O)=S.NP(O)(O)=S.NP(O)(O)=S.NP(O)(O)=S

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601 0.94
Ammonia Solution, Strong SCHEMBL11778482 0.89
Hydrochloric Acid SCHEMBL11432293 0.89
SCHEMBL31429596 0.89
Ammonia Solution, Strong SCHEMBL28610204 0.89
Hydrochloric Acid SCHEMBL11037230 0.89
Ethylene SCHEMBL27984056 0.84
SCHEMBL1776917 0.82
Phosphoramidic Acid SCHEMBL1425025 0.80 CA2 (0.36)
Hydrochloric Acid SCHEMBL11428331 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588472-A1 NOVEL AMINOTHIOL REDUCTION OF ISCHEMIA-REPERFUSION-INDUCED CELL DEATH Obvia Pharmaceuticals Ltd. (US) 2025-07-23 EP disclosed
US-11690813-B2 Aminothiol reduction of ischemia-reperfusion-induced cell death Obvia Pharmaceuticals Ltd (US) 2023-07-04 US disclosed
US-20210299066-A1 NOVEL AMINOTHIOL REDUCTION OF ISCHEMIA-REPERFUSION-INDUCED CELL DEATH Obvia Pharmaceuticals Ltd 2021-09-30 US disclosed
EP-3758691-A1 NOVEL AMINOTHIOL REDUCTION OF ISCHEMIA-REPERFUSION-INDUCED CELL DEATH Suzhou NG Biomedicine Co., Ltd. (CN) 2021-01-06 EP disclosed
US-20170065541-A1 SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMINOTHIOL RADIOPROTECTORS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-03-09 US disclosed
US-9458100-B2 Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-10-04 US disclosed
US-20160243062-A1 SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMINOTHIOL RADIOPROTECTORS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-08-25 US disclosed
US-20140107217-A1 SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMlNOTHIOL RADIOPROTECTORS WISCONSIN ALUMNI RESEARCH FOUNDATION 2014-04-17 US disclosed
US-20140107216-A1 SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMlNOTHIOL RADIOPROTECTORS WISCONSIN ALUMNI RESEARCH FOUNDATION 2014-04-17 US disclosed