Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465007 | 0.85 | NR1D1 (0.42) | — | |
| SCHEMBL14097932 | 0.84 | POLB (0.43) | ACE | |
| SCHEMBL4598286 | 0.84 | POLB (0.43) | ACE | |
| SCHEMBL4597401 | 0.83 | NR1D1 (0.40) | HRH1 | |
| SCHEMBL17094798 | 0.83 | POLB (0.42) | ACE | |
| SCHEMBL1769827 | 0.82 | NR1D1 (0.42) | HRH1 | |
| SCHEMBL17062258 | 0.80 | SMN1; SMN2 (0.40) | ACE | |
| SCHEMBL16465441 | 0.76 | ACE (0.44) | ACE | |
| SCHEMBL16465438 | 0.76 | ACE (0.44) | ACE | |
| SCHEMBL18419569 | 0.76 | DPP8 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906559-A1 | AZAINDOLINES | F. Hoffmann-La Roche AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014056871-A1 | AZAINDOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | disclosed |