Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.62 |
| ▸ | KDR | P35968 | 4/20 | 0.62 |
| ▸ | SRC | P12931 | 3/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839424 | 0.77 | BRAF (1.00) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL1647214 | 0.72 | KDR (0.72) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL1646508 | 0.71 | SRC (0.61) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL5352369 | 0.70 | BRAF (0.61) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL5356381 | 0.69 | KDR (0.52) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL1646015 | 0.69 | MAPK14 (0.59) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL5257540 | 0.69 | CSNK1D (1.00) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL5698604 | 0.69 | CSNK1D (1.00) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL1648069 | 0.68 | MAPK14 (0.67) | BRAFKDRSRCMAPK14CSNK1D | |
| SCHEMBL1648432 | 0.67 | CSNK1D (0.56) | BRAFKDRSRCMAPK14CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |