Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.67 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.67 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.67 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.67 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.67 |
| ▸ | BRAF | P15056 | 5/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646042 | 0.85 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5698604 | 0.80 | CSNK1D (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL5257540 | 0.80 | CSNK1D (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1647080 | 0.78 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL990036 | 0.75 | KDM4E (0.40) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1646015 | 0.74 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1647091 | 0.74 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1645793 | 0.73 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL16105481 | 0.73 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1647505 | 0.73 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |