Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28222242 | 0.91 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2DPP4DPP8L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2989718 | 0.87 | ALDH1A1 (0.44) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL8721639 | 0.84 | ALDH1A1 (0.42) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL28293684 | 0.84 | ALDH1A1 (0.42) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL1505073 | 0.84 | ALDH1A1 (0.42) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL1035693 | 0.82 | TP53 (0.42) | ALDH1A1DPP4DPP8L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL2299667 | 0.82 | DPP4 (0.36) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL2566861 | 0.82 | DPP4 (0.36) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL4431540 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2DPP4DPP8L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28538609 | 0.81 | ALDH1A1 (0.35) | ALDH1A1DPP4DPP8L3MBTL1KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723323-B1 | LYOPHILIZATION OF SYNTHETIC LIPOSOMAL PULMONARY SURFACTANT | DISCOVERY LAB INC (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-2837377-A1 | Lyophilization of synthetic liposomal pulmonary surfactant | Discovery Laboratories, Inc. (US) | 2015-02-18 | — | — | EP | disclosed |