Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329442 | 0.86 | GCK (0.59) | GCK | |
| SCHEMBL16467338 | 0.85 | GCK (0.62) | GCK | |
| SCHEMBL16467529 | 0.85 | GCK (0.64) | GCK | |
| SCHEMBL2660591 | 0.84 | GCK (0.58) | GCK | |
| SCHEMBL2656048 | 0.83 | GCK (0.56) | GCK | |
| SCHEMBL16467471 | 0.82 | GCK (0.57) | GCK | |
| SCHEMBL16467424 | 0.82 | GCK (0.53) | GCK | |
| SCHEMBL16467279 | 0.81 | GCK (0.56) | GCK | |
| SCHEMBL16467347 | 0.81 | GCK (0.54) | GCK | |
| SCHEMBL2656156 | 0.81 | GCK (0.54) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | claimed |