Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595423 | 0.87 | GCK (0.59) | GCK | |
| SCHEMBL16467338 | 0.87 | GCK (0.62) | GCK | |
| SCHEMBL16467529 | 0.85 | GCK (0.64) | GCK | |
| SCHEMBL2656048 | 0.84 | GCK (0.56) | GCK | |
| SCHEMBL16467486 | 0.84 | GCK (0.58) | GCK | |
| SCHEMBL16467471 | 0.83 | GCK (0.57) | GCK | |
| SCHEMBL16467347 | 0.82 | GCK (0.54) | GCK | |
| SCHEMBL16467279 | 0.82 | GCK (0.56) | GCK | |
| Hydrochloric Acid SCHEMBL2657431 | 0.82 | GCK (0.56) | GCK | |
| SCHEMBL16467450 | 0.81 | GCK (0.55) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173745-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008118718-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2008-10-02 | — | — | WO | disclosed |