Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 7/20 | 0.77 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.77 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468722 | 1.00 | PIM1 (0.77) | PIM1PIM2PIM3POLBGPR119 | |
| SCHEMBL12282933 | 1.00 | PIM1 (0.77) | PIM1PIM2PIM3POLBGPR119 | |
| SCHEMBL2426642 | 0.95 | PIM2 (0.69) | PIM1PIM2PIM3POLBBTK | |
| SCHEMBL2426644 | 0.95 | PIM2 (0.69) | PIM1PIM2PIM3POLBBTK | |
| SCHEMBL2426637 | 0.95 | PIM2 (0.69) | PIM1PIM2PIM3POLBBTK | |
| SCHEMBL2426638 | 0.95 | PIM2 (0.69) | PIM1PIM2PIM3POLBBTK | |
| SCHEMBL13538032 | 0.93 | PIM1 (0.74) | PIM1PIM2PIM3POLBGPR119 | |
| SCHEMBL2420001 | 0.88 | PIM2 (0.68) | PIM1PIM2PIM3BTK | |
| SCHEMBL2426038 | 0.88 | PIM2 (0.68) | PIM1PIM2PIM3BTK | |
| SCHEMBL2429998 | 0.87 | PIM1 (0.75) | PIM1PIM2PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150051185-A1 | Chemical Compounds 251 | ASTRAZENECA AB (SE) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051185-A1 | Chemical Compounds 251 | PIM1, PIM3, PIM2 | PIM1 1/4885PIM2 3/4885PIM3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.