Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16469464 | 1.00 | PRCP (0.44) | PRCPDPP7KDM4EHTR2CCTSC | |
| Hydrochloric Acid SCHEMBL17222185 | 0.98 | PRCP (0.43) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL7385460 | 0.83 | PRCP (0.48) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL7385456 | 0.83 | PRCP (0.48) | PRCPDPP7KDM4EHTR2CCTSC | |
| Hydrochloric Acid SCHEMBL7388975 | 0.81 | PRCP (0.47) | PRCPDPP7KDM4EHTR2CCTSC | |
| Hydrochloric Acid SCHEMBL7388972 | 0.81 | PRCP (0.47) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL27284993 | 0.81 | PRCP (0.45) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL495672 | 0.79 | L3MBTL1 (0.54) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL17676963 | 0.79 | L3MBTL1 (0.54) | PRCPDPP7KDM4EHTR2CCTSC | |
| SCHEMBL1983142 | 0.79 | L3MBTL1 (0.54) | PRCPDPP7KDM4EHTR2CCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180325893-A1 | SUBACUTE ADMINISTRATION OF NMDA MODULATORS ALONE OR IN COMBINATION | UNIV NORTHWESTERN (US) | 2018-11-15 | — | — | US | disclosed |
| EP-2771021-B1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTH WESTERN UNIV (US) | 2018-08-29 | — | — | EP | disclosed |
| US-20180237474-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | INNOVIVA TRC HOLDINGS LLC | 2018-08-23 | — | — | US | disclosed |
| US-20160368947-A1 | NMDA Receptor Modulators and Uses Thereof | INNOVIVA TRC HOLDINGS LLC | 2016-12-22 | — | — | US | disclosed |
| US-20150315237-A1 | NMDA Receptor Modulators and Uses Thereof | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | PRCP 1775/4885DPP7 1502/4885KDM4E 1522/4885 |
| US-20150315237-A1 | NMDA Receptor Modulators and Uses Thereof | GRIN1, GRIN2A, GRIN3A | PRCP 1775/4885DPP7 1502/4885KDM4E 1522/4885 |
| US-20160368947-A1 | NMDA Receptor Modulators and Uses Thereof | GRIN1, GRIN2A, GRIN3A | PRCP 1775/4885DPP7 1502/4885KDM4E 1522/4885 |
| US-20180325893-A1 | SUBACUTE ADMINISTRATION OF NMDA MODULATORS ALONE OR IN COMBINATION | GRIN2A, GRIN2D, GRIN1 | PRCP 1880/4885DPP7 3634/4885KDM4E 1657/4885 |
| US-20180237474-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | PRCP 1775/4885DPP7 1502/4885KDM4E 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.