⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525914 | 0.81 | — | — | |
| SCHEMBL7519504 | 0.81 | — | — | |
| SCHEMBL33498 | 0.81 | — | — | |
| SCHEMBL10754954 | 0.78 | PARP1 (0.33) | — | |
| SCHEMBL840269 | 0.78 | — | — | |
| SCHEMBL4640334 | 0.78 | — | — | |
| SCHEMBL1029023 | 0.77 | — | — | |
| SCHEMBL19550942 | 0.77 | — | — | |
| SCHEMBL10755272 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1291117 | 0.76 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113891879-A | 3, 6-disubstituted-2-pyridine aldoxime skeletons | 国家科学研究中心 | 2022-01-04 | — | — | CN | claimed |
| CN-113891879-B | 3, 6-Disubstituted-2-pyridine aldoxime skeleton | 国家科学研究中心 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552094-A | HDAC inhibitors, methods of making and uses thereof | 安徽中医药大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-113845439-B | Bisbenzylamide CXCR4 antagonist and preparation and application thereof | 杭州师范大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-115710287-B | Ring-opening boronation reaction method for cyclopropane compound under no metal catalysis | 中国科学院兰州化学物理研究所 | 2024-01-09 | — | — | CN | disclosed |
| CN-109415334-B | Process for producing 1, 3-dioxane-5-ones | 花王株式会社 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023217018-A1 | EZH2 INHIBITOR AND USE THEREOF IN MEDICINE | 贝达药业股份有限公司 | 2023-11-16 | — | — | WO | disclosed |
| CN-116730995-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115710287-A | Ring-opening boronization reaction method of cyclopropane compound under condition of no metal catalysis | 中国科学院兰州化学物理研究所 | 2023-02-24 | — | — | CN | disclosed |
| CN-113891879-A | 3, 6-disubstituted-2-pyridine aldoxime skeletons | 国家科学研究中心 | 2022-01-04 | — | — | CN | disclosed |
| CN-110191722-A | Pharmaceutical composition for treating HTLV-1 related myelopathy | 第一三共株式会社 | 2019-08-30 | — | — | CN | disclosed |
| CN-109988199-A | Rhodioside derivative and application thereof | 上海华汇拓医药科技有限公司 | 2019-07-09 | — | — | CN | disclosed |
| US-9309218-B2 | 2-Oxo-1,3-dioxolane-4-carboxamides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| CN-102442970-A | Thiazole compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB | 2012-05-09 | — | — | CN | disclosed |
| CN-101454302-A | Thiazole compounds as cannabinoid receptor ligands and uses thereof | ABBOTT LAB (US) | 2009-06-10 | — | — | CN | disclosed |
| CN-1166678-C | Purine derivatives | ������ҩ������˾ | 2004-09-15 | — | — | CN | disclosed |
| CN-1400975-A | Purine derivatives | PFIZER LTD (US) | 2003-03-05 | — | — | CN | disclosed |
| CN-1378551-A | Purine derivatives | PFIZER LTD (US) | 2002-11-06 | — | — | CN | disclosed |