⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519504 | 1.00 | — | — | |
| SCHEMBL33498 | 1.00 | — | — | |
| SCHEMBL10754954 | 0.97 | PARP1 (0.33) | — | |
| Bicarbonate SCHEMBL5246269 | 0.94 | ACHE (0.33) | — | |
| SCHEMBL28098572 | 0.87 | — | — | |
| SCHEMBL16469722 | 0.81 | — | — | |
| Phenol SCHEMBL11179725 | 0.79 | TDP1 (0.46) | — | |
| SCHEMBL4640334 | 0.79 | — | — | |
| SCHEMBL840269 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1291117 | 0.77 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792876-A2 | Process for preparing 1,5-benzothiazepine derivative | TANABE SEIYAKU CO., LTD. (JP) | 1997-09-03 | — | — | EP | claimed |
| US-8648189-B2 | Method for the preparation of rivoraxaban | SANDOZ AG (CH) | 2014-02-11 | — | — | US | disclosed |
| US-20130184457-A1 | METHOD FOR THE PREPARATION OF RIVORAXABAN | SANDOZ AG (CH) | 2013-07-18 | — | — | US | disclosed |
| EP-2521717-B1 | Method for the preparation of rivaroxaban | SANDOZ AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| EP-2521717-A1 | METHOD FOR THE PREPARATION OF RIVAROXABAN | Sandoz AG (CH) | 2012-11-14 | — | — | EP | disclosed |
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-1999007875-A1 | PROCESS FOR PREPARING (2R,3S)-3-(SUBSTITUTED OR UNSUBSTITUTED PHENYL)GLYCIDAMIDE COMPOUNDS BY ASYMMETRIC AMIDATION | TANABE SEIYAKU CO., LTD. (JP) | 1999-02-18 | — | — | WO | disclosed |
| US-5847122-A | Process for preparing 1,5-benzothiazepine derivative | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0792876-A2 | Process for preparing 1,5-benzothiazepine derivative | TANABE SEIYAKU CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |