Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 14/20 | 0.41 |
| ▸ | JAK3 | P52333 | 11/20 | 0.38 |
| ▸ | JAK1 | P23458 | 8/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 5/20 | 0.38 |
| ▸ | PAK4 | O96013 | 5/20 | 0.38 |
| ▸ | RET | P07949 | 5/20 | 0.38 |
| ▸ | LTK | P29376 | 5/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.38 |
| ▸ | CLK2 | P49760 | 5/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 5/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 5/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646367 | 0.88 | JAK2 (0.41) | MAPK14JAK2JAK3JAK1DAPK3 | |
| SCHEMBL1647776 | 0.87 | MAPK14 (0.59) | MAPK14CSNK1DMAPK11ROCK1AURKA | |
| SCHEMBL1647208 | 0.75 | MAPK14 (0.51) | MAPK14CSNK1DMAPK11KDRBRAF | |
| SCHEMBL1648278 | 0.75 | AURKB (0.48) | MAPK14CSNK1DMAPK11ROCK1AURKA | |
| SCHEMBL1645070 | 0.75 | CSNK1D (0.42) | MAPK14CSNK1DMAPK11ABL1BRAF | |
| SCHEMBL1645407 | 0.73 | BRAF (0.37) | MAPK14CSNK1DMAPK11CSNK1A1MAP4K4 | |
| SCHEMBL16105443 | 0.73 | MAPK14 (0.53) | MAPK14CSNK1DMAPK11JAK2JAK3 | |
| SCHEMBL1647326 | 0.73 | MAPK14 (0.43) | MAPK14CSNK1DMAPK11AURKAKDR | |
| SCHEMBL1646713 | 0.73 | CSNK1D (0.44) | MAPK14CSNK1DMAPK11KDRABL1 | |
| SCHEMBL26113804 | 0.73 | ABL1 (0.38) | MAPK14ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |