Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 9/20 | 0.48 |
| ▸ | AURKA | O14965 | 8/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648278 | 0.88 | AURKB (0.48) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL1647002 | 0.87 | MAPK14 (0.42) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL1646703 | 0.84 | NUDT1 (0.53) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL1648143 | 0.83 | BRAF (0.46) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL1647326 | 0.83 | MAPK14 (0.43) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL16655277 | 0.80 | AURKB (0.44) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL16655108 | 0.80 | AURKB (0.42) | MAPK14CSNK1DMAPK11AURKBAURKA | |
| SCHEMBL16655428 | 0.79 | AURKB (0.46) | AURKBAURKAPIK3C3INCENPLYN | |
| SCHEMBL1647208 | 0.78 | MAPK14 (0.51) | MAPK14CSNK1DMAPK11BRAFMAPK13 | |
| SCHEMBL16655062 | 0.77 | AURKB (0.57) | AURKBAURKAPIK3C3INCENPIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |