SCHEMBL1647140

SCHEMBL1647140

Clc1cccc(CCSSCCc2cccc(Cl)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.63
PNMT P11086 2/20 0.56
HTR3E A5X5Y0 3/20 0.53
HTR3B O95264 3/20 0.53
HTR3A P46098 3/20 0.53
HTR3D Q70Z44 3/20 0.53
HTR3C Q8WXA8 3/20 0.53
AOC3 Q16853 1/20 0.53
IDO1 P14902 3/20 0.50
CYP3A4 P08684 2/20 0.50
AGXT P21549 2/20 0.50
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6011476 0.86 TAAR1 (0.63) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL12050856 0.85 TAAR1 (0.74) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL21726756 0.83 TAAR1 (0.59) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL5241228 0.81 TAAR1 (0.68) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL27650757 0.79 TAAR1 (0.55) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL23071686 0.79 TAAR1 (0.65) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL3084324 0.79 TAAR1 (0.65) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL31567921 0.79 TAAR1 (0.65) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL2803352 0.79 IDO1 (0.58) TAAR1PNMTHTR3EHTR3BHTR3A
SCHEMBL1646153 0.78 TSHR (0.42) TAAR1PNMTAOC3IDO1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed