SCHEMBL1646153

SCHEMBL1646153

Clc1cc(Cl)cc(CCSSCCc2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
IDO1 P14902 4/20 0.41
DAO P14920 1/20 0.38
TAAR1 Q96RJ0 3/20 0.37
PNMT P11086 1/20 0.34
CNR1 P21554 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6011634 0.84 TSHR (0.42) TSHRIDO1DAOTAAR1PNMT
SCHEMBL2355446 0.80 TSHR (0.57) TSHRIDO1DAOTAAR1PNMT
SCHEMBL1647140 0.78 TAAR1 (0.63) IDO1DAOTAAR1PNMTHDAC3
SCHEMBL5977021 0.77 IDO1 (0.35) TSHRIDO1DAOTAAR1PNMT
SCHEMBL1646290 0.74 IDO1 (0.55) IDO1TAAR1AOC3
SCHEMBL1645349 0.74 IDO1 (0.39) IDO1TAAR1
SCHEMBL5980447 0.72 PNMT (0.35) TSHRIDO1DAOTAAR1PNMT
SCHEMBL16235640 0.72 DAO (0.35) TSHRIDO1DAOCNR1
SCHEMBL1648004 0.72 ALDH1A1 (0.39) TSHRTAAR1TP53CYP3A4
SCHEMBL1570285 0.70 TAAR1 (0.60) TSHRIDO1TAAR1PNMTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed