SCHEMBL1647207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15927312	0.94	PSEN1 (0.46)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL28110781	0.85	PSEN1 (0.55)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL16333479	0.82	TSHR (0.59)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL27331094	0.82	PSEN1 (0.54)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL1753984	0.82	PSEN1 (0.54)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL29843316	0.82	CA1 (0.38)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL13036990	0.81	PSEN1 (0.53)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL13037002	0.78	PSEN1 (0.50)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL13154400	0.78	PSEN1 (0.50)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL28723339	0.77	CHRNB2 (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.