Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165798 | 0.85 | EPHB4 (0.49) | DEGS1MAPTKDM4EGAALMNA | |
| SCHEMBL247457 | 0.84 | GAA (0.39) | DEGS1MAPTKDM4EGAALMNA | |
| SCHEMBL12019745 | 0.81 | HCAR3 (0.46) | DEGS1MAPTKDM4EGAALMNA | |
| SCHEMBL29525907 | 0.79 | PTGS1 (0.53) | DEGS1MAPTGAALMNAMEN1 | |
| SCHEMBL587272 | 0.79 | PTGS1 (0.53) | DEGS1MAPTGAALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL30062287 | 0.78 | PTGS1 (0.51) | DEGS1MAPTGAALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL15167588 | 0.78 | PTGS1 (0.51) | DEGS1MAPTGAALMNAMEN1 | |
| SCHEMBL25096472 | 0.76 | DEGS1 (0.41) | DEGS1MAPTKDM4EGAALMNA | |
| SCHEMBL18932624 | 0.76 | DEGS1 (0.44) | DEGS1MAPTGAALMNAMEN1 | |
| SCHEMBL12293177 | 0.76 | HCAR3 (0.50) | DEGS1MAPTGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215006-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | WASHINGTON STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-9328129-B2 | Peptidomimetic inhibitors of PSMA | WASHINGTON STATE UNIVERSITY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140010758-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | THE REGEANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215006-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | PSMA1, PSMA3, PSMA2 | DEGS1 3274/4885MAPT 788/4885KDM4E 3239/4885 |
| US-20140010758-A1 | PEPTIDOMIMETIC INHIBITORS OF PSMA | PSMA1, PSMA3, PSMA2 | DEGS1 3274/4885MAPT 788/4885KDM4E 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.