SCHEMBL16472899

SCHEMBL16472899

c1ccc(-n2c3ccccc3c3cc4c(-c5cccnc5)cc5cc6sc7ccccc7c6cc5c4cc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.42
MAPT P10636 4/20 0.36
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
CYP11B2 P19099 3/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
P4HTM Q9NXG6 1/20 0.32
HIPK2 Q9H2X6 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16472895 1.00 CYP11B1 (0.42) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL15461875 0.90 CYP11B1 (0.49) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL14725692 0.90 CYP11B1 (0.49) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL15912237 0.90 CYP11B1 (0.49) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL16472860 0.87 CYP11B1 (0.40) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL16472851 0.87 CYP11B1 (0.40) CYP11B1MAPTKDM4EATML3MBTL1
SCHEMBL16472901 0.86 L3MBTL1 (0.40) MAPTKDM4EATML3MBTL1RAB9A
SCHEMBL16472908 0.86 L3MBTL1 (0.40) MAPTKDM4EATML3MBTL1RAB9A
SCHEMBL13820437 0.85 CYP11B1 (0.45) CYP11B1MAPTGPR84CYP11B2NPC1
SCHEMBL15912270 0.85 CYP11B1 (0.55) CYP11B1MAPTKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9118021-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-25 US disclosed
US-9118021-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-25 US disclosed
US-20140103300-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-04-17 US disclosed
US-20140103300-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-04-17 US disclosed