Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | RHOC | P08134 | 8/20 | 0.34 |
| ▸ | RHOA | P61586 | 8/20 | 0.34 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431294 | 0.81 | AR (0.37) | ARPGRRORC | |
| SCHEMBL2435565 | 0.78 | STAT3 (0.41) | ARPGRRORC | |
| SCHEMBL16472960 | 0.78 | GAA (0.36) | — | |
| SCHEMBL2433297 | 0.77 | AR (0.38) | ARPGRRORC | |
| SCHEMBL2427584 | 0.76 | AR (0.37) | ARPGRRORC | |
| SCHEMBL12292864 | 0.76 | POLB (0.43) | ARPGRRORC | |
| SCHEMBL4552329 | 0.73 | AR (0.40) | ARPGRRORC | |
| SCHEMBL2431035 | 0.73 | AR (0.43) | ARPGRRORC | |
| SCHEMBL16473021 | 0.73 | PGR (0.41) | ARPGR | |
| SCHEMBL16473033 | 0.71 | AR (0.43) | ARPGRRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079466-B1 | SUBSTITUTED INDOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2014-01-15 | — | — | EP | disclosed |