Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884196 | 0.80 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7884123 | 0.78 | PDE9A (0.71) | PDE9A | |
| SCHEMBL7880383 | 0.77 | PDE9A (0.77) | PDE9A | |
| SCHEMBL7876055 | 0.77 | PDE9A (0.84) | PDE9A | |
| SCHEMBL7876909 | 0.77 | PDE9A (1.00) | PDE9A | |
| SCHEMBL16473822 | 0.77 | PDE9A (0.69) | PDE9A | |
| SCHEMBL7879280 | 0.76 | PDE9A (0.82) | PDE9A | |
| SCHEMBL7881319 | 0.76 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7884512 | 0.76 | PDE9A (1.00) | PDE9A | |
| SCHEMBL7890325 | 0.76 | PDE9A (0.70) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414363-B1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS PDE9A MODULATORS | BOEHRINGER INGELHEIM INT (DE) | 2014-01-08 | — | — | EP | disclosed |