Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267415 | 0.91 | HDAC1 (0.57) | NAMPTCYP2C9HDAC1HDAC3HDAC2 | |
| SCHEMBL6885554 | 0.88 | IDO1 (0.66) | HDAC1HDAC3HDAC2 | |
| SCHEMBL16108694 | 0.82 | NAMPT (0.79) | NAMPTCYP2C9 | |
| SCHEMBL1647859 | 0.81 | NAMPT (0.71) | NAMPTCYP2C9HDAC1HDAC3HDAC2 | |
| SCHEMBL25853566 | 0.78 | NAMPT (0.63) | NAMPTCYP2C9HDAC1HDAC3HDAC2 | |
| SCHEMBL12779529 | 0.78 | ROCK2 (0.66) | — | |
| SCHEMBL15243588 | 0.77 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL28086946 | 0.77 | NAMPT (0.80) | NAMPTCYP2C9HDAC1HDAC3HDAC2 | |
| SCHEMBL15246211 | 0.77 | NAMPT (0.76) | NAMPTCYP2C9HDAC1HDAC3HDAC2 | |
| SCHEMBL160706 | 0.77 | NAMPT (1.00) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |