Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647535 | 0.77 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL2231864 | 0.70 | POLB (0.47) | MAPTALDH1A1POLBSMN1; SMN2CYP1A2 | |
| SCHEMBL942774 | 0.66 | MAPT (0.52) | MAPTALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL2231547 | 0.65 | MAPT (0.48) | MAPTALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL942649 | 0.65 | MAPT (0.45) | MAPTALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL943658 | 0.64 | MAPT (0.57) | MAPTALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL9189686 | 0.63 | MAPT (0.50) | MAPTALDH1A1TDP1CYP1A2CYP3A4 | |
| SCHEMBL1644973 | 0.63 | MAPT (0.39) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL2231651 | 0.63 | MAPT (0.42) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL19833069 | 0.63 | NPC1 (0.48) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |